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Masterclass: Diseases of the ageing brain

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25.01.2022 So you think you know Alzheimers, maybe not... Alzheimers aint Alzheimers The Subtypes Whilst Alzheimers pathology represents the most common neurodegenerative condition seen in the elderly, in the absence of a diagnostic test it can often be difficult to make the diagnosis. This lecture will consider the question of one pathology manifesting as differing clinical phenotypes and will address diagnostic pointers as well as approaches to management.... Associate Professor Michael Woodward is Head of Aged Care Research and the Memory Clinic at Austin Health in Melbourne, Victoria. He is a specialist in geriatric medicine with major interests in the treatment of Alzheimers disease (AD) and other dementias. He is Principal Investigator for numerous research trials of new therapies for AD and related disorders. He is immediate Past President of the AC4R the Australasian Consortium of Centres for Clinical Cognitive Research that brings together researchers into therapeutic agents for dementia. He is also a member of the Alzheimers Australia Vic Board, being appointed their chief medical advisor and chairing their research foundation, which administers over $2 million of research funding. Michael Woodwards publication record includes over 100 original research and review articles. He has been awarded his MD on the overlap between the dementia syndromes. More recent research interests have focussed on characterizing the frontal variant of Alzheimers Disease. He is a Fellow of the Australian Association of Gerontology (AAG), the Australian and New Zealand Society for Geriatric Medicine, the Australian Wound Management Association (AWMA) and the Royal Australasian College of Physicians (RACP) and has long served each of these professional bodies, including becoming President of AWMA and AAG (Vic) and chairing the Committee for Physician Training that oversaw the training of all RACP trainees.

25.01.2022 Gearing up for Day 2 of Master Class 2016 in Sydney! Check out the photos from Day 1 and feel free to tag yourself and friends.

25.01.2022 Check out the Giants of Geriatrics course https://hunterpostgrad.wixsite.com/gog2018

22.01.2022 Thank you for all coming to this year's Master Class. The photos have now been uploaded for you to enjoy. Look out for the notifications about updated content through the myinteract app. Next year's dates are locked in for October 13/14th and please give us your suggestions for the program through the app. Follow @profsimonlewis on Twitter and look out for #MasterClassAgeingBrain to keep in touch.

21.01.2022 Thank you all for your participation in Master Class 2016. We hope you all had a safe journey home despite the weather issues around the country. We look forward to having you all back again next year. Please lock in your diaries: Master Class: Diseases of the Ageing Brain 2017... October 7th and 8th, 2017 See more

21.01.2022 A/Professor Michael Woodward MB BS MD FRACP Head of Aged Care Research and Memory Clinic, Austin Health, Heidelberg, VIC. Associate Professor Michael Woodward is Head of Aged Care Research and the Memory Clinic at Austin Health in Melbourne, Victoria. He is a specialist in geriatric medicine with major interests in the treatment of Alzheimers disease (AD) and other dementias. He is Principal Investigator for numerous research trials of new therapies for AD and related disord...Continue reading

21.01.2022 Who better to talk about Stroke than Bruce Campbell: A/Prof Bruce Campbell is a consultant neurologist and Head of Hyperacute Stroke in the Department of Neurology, Royal Melbourne Hospital. He is a principal research fellow in the Melbourne Brain Centre @ RMH, Department of Medicine, University of Melbourne. His research interests are focused on the imaging and treatment of acute stroke and led the EXTEND-IA trial of endovascular clot retrieval (NEJM 2015). He is also a Chai...r of Clinical Council and a director of the Stroke Foundation. He has been an inaugural member of the Victorian stroke telemedicine project and is the co-ordinator of the National Brainschool training program for neurologists in training. Managing Acute Stroke The last few years have seen dramatic advances in the treatment of ischemic stroke. This talk will cover the latest in thrombolysis and thrombectomy for ischemic stroke, secondary prevention and the potential for treatment of intracerebral hemorrhage. When do white matter lesions matter? Incidental white matter lesions are a common cause of referral to neurologists. There is remarkably little evidence to guide management. This talk will discuss the potential causes of white matter lesions and an approach to management of small vessel disease.

20.01.2022 Just over a month before the Master Class. Places are filling up fast, so please don't miss out on this amazing program: Saturday 07 October Session I... PROFESSOR SHARON NAISMITH, BRAIN AND MIND CENTRE (UNIVERSITY OF SYDNEY) - ASSESSING COGNITION IN THE CLINIC PROFESSOR SIMON LEWIS, BRAIN AND MIND CENTRE (UNIVERSITY OF SYDNEY) - EXAMINING FOR HIGHER ORDER SIGNS Session II - CASES: PANEL DISCUSSION (CHAIR SIMON LEWIS) DR JAMES BURRELL, NEUROSCIENCE RESEARCH AUSTRALIA (NeuRA) AND CONCORD HOSPITAL ASSOCIATE PROFESSOR MICHAEL WOODWARD, AUSTIN HEALTH PROFESSOR CARMELLE PEISAH, CONJOINT PROFESSOR UNSW, CLINICAL ASSOCIATE PROFESSOR (UNIVERSITY OF SYDNEY) Session III A/PROFESSOR BRUCE CAMPBELL, ROYAL MELBOURNE HOSPITAL AND UNIVERSITY OF MELBOURNE - MANAGING ACUTE STROKE A/PROFESSOR BRUCE CAMPBELL ROYAL MELBOURNE HOSPITAL AND UNIVERSITY OF MELBOURNE - WHEN DO WHITE MATTER LESIONS MATTER? Session IV DR LYNETTE MASTERS, SOUTHERN RADIOLOGY, BRAIN AND MIND CENTRE - NEURORADIOLOGY 1.02: SPECIFIC PATTERNS OF NEUROPATHOLOGY DR DEV BANERJEE, WOOLCOCK INSTITUTE - MANAGING SLEEP WAKE DISTURBANCES IN THE ELDERLY Sunday 08 October Session V PROFESSOR JACQUELINE CLOSE, PRINCE OF WALES HOSPITAL AND UNIVERSITY OF NEW SOUTH WALES - MANAGING FALLS PROFESSOR SIMON LEWIS, BRAIN AND MIND CENTRE, THE UNIVERSITY OF SYDNEY - MINISTRY OF FUNNY WALKS ASSESSING GAIT Session VI PROFESSOR HENRY BRODATY, CENTRE FOR HEALTHY BRAIN AGEING, UNSW - PRACTICAL ASSESSMENT AND MANAGEMENT OF BPSD ASSOCIATE PROFESSOR MICHAEL WOODWARD, AUSTIN HEALTH - ALZHEIMER'S AIN'T ALZHEIMER'S - THE SUBTYPES

20.01.2022 Check out this opportunity to learn more about curing Alzheimer's https://www.trybooking.com/383961

20.01.2022 Registrations have now opened for Master Class 2018, October 13th and 14th: https://sydney.edu.au//masterclass-diseases-of-the-ageing- Please circulate this link to your colleagues. Look forward to seeing you all in October!

18.01.2022 Professor Halmagyi received his BSc (Med) at the University of Sydney in 1968. He continued his studies at the University with a MBBS in 1971 and later his MD in 1995. He was appointed as a Consultant Neurologist at the RPAH in 1979 and continues to hold this position today. In 1998 he was appointed Clinical Professor of Neurology at the University of Sydney. Today at the RPAH he is the director of the Eye and Ear Research Unit which is the national referral centre for the di...agnosis and treatment of patients from all over Australia with difficult balance disorders. Gabor Michael Halmagyi has received many awards for his work including the Research Achievement Award from the RPAH in 1996 and the Hallpike Nylen Prize from the Barany Society in 1996. The Halmagyi-Curthoys head impulse sign is now known and used around the world as a very quick, simple and effective indicator of the functional level of semicircular canal functioning. This test can be conducted in the clinic or even at the bedside and is now probably the most widely used clinical indicator of vestibular function in the world today since it costs nothing, is fast, simple and safe and gives such valuable diagnostic information instantly. That test was developed with NHMRC support. Falling and a fear of falling are very common in the elderly and can arise from multiple causes. This presentation will allow the clinician to help dissociate peripheral from central causes of imbalance. The content will focus on bedside assessment and how it may best be supplemented by specialist investigations. Finally, the lecture will guide clinicians through practical treatment strategies.

17.01.2022 Dr James Burrell graduated from Arts/Medicine with Honours at UNSW in 2000. James received clinical training in medicine and neurology at Prince of Wales, Royal Prince Alfred, and Concord Hospitals in Sydney, becoming a Fellow of the Royal Australasian College of Physicians in 2008. James was awarded a scholarship from the MNDRIA and the NHMRC for a PhD with Professors John Hodges and Matthew Kiernan, which he completed in 2012. He was awarded an NHMRC Early Career Fellowshi...p in 2013 and researches the overlaps between frontotemporal dementia and motor neuron disease, as well as young-onset and atypical dementia syndromes at NeuRA in Sydney. James also runs a busy Early-Onset Dementia clinic at Concord Hospital, where is employed as Staff Specialist in neurology. NEUROLOGICAL EXAMINATION IN THE COGNITIVE CLINIC The neurological examination may offer important clues to the diagnosis in neurodegenerative diseases. Here, Dr Burrell outlines a practical approach to the neurological examination in patient who are referred to the cognitive clinic. Emphasis will be placed on the examination of the motor system (i.e., pyramidal, anterior horn cell, and extrapyramidal signs) and apraxia, as well as eye movement disturbances. HOW DO I EXAMINE SPEECH & LANGUAGE A clear approach to the assessment of language is critical to help develop a differential diagnosis in cases of primary progressive aphasia and other dementias. Here Dr Burrell outlines his approach to the clinical assessment, and basic classification, of speech and language disorders in the cognitive clinic. He will attempt to answer the following questions; what does semantic dementia sound like in the clinic? What is the difference between fluent and non-fluent aphasia, and can I classify this patient's language disorder more specifically? When should I worry about the development of motor neuron disease in my patient with dementia?

17.01.2022 Master Class 2018 is fast approaching so Register to day and don't miss Lynette Masters with her approach to imaging the brain and spine!

16.01.2022 Falls and fall related injury continue to be a significant problem for older people despite a large evidence base to support preventive strategies. Cognition plays a crucial role both in terms of risk factors for falls but also in the approach taken to assess, manage and prevent falls and fall related injury. This presentation will cover common risk factors for falls and evidence based intervention strategies. It will then focus on preventing falls in people with dementia, hi...ghlighting ongoing research in this field. Jacqui Close is a consultant in Orthogeriatrics at the Prince of Wales Hospital in Sydney and Clinical Director of the Falls, Balance and Injury Research Centre at Neuroscience Research Australia. She trained in the UK and moved to Australia in 2005. Her research interests range from injury epidemiology, to intervention studies and implementation research. She has published over 150 papers and her research is currently focused on injury prevention in dementia, hip fracture care and care of older people in surgery. She sits on a number of State and National committees in relation to Aged Health, is the Co-Chair of the ANZ Hip Fracture Registry Steering Group.

16.01.2022 So you think you know about Capacity? Great online resource for healthcare professionals from one of the stars of our Master Class, Prof Carmelle Peisah. You will definitely up-skill in 30 minutes: http://capacityaustralia.org.au/globalcapacity/

15.01.2022 Sarah Hilmer (MBBS FRACP PhD) is Professor of Geriatric Pharmacology at the University of Sydney and Head of Department of Clinical Pharmacology and Senior Staff Specialist in Aged Care at Royal North Shore Hospital. She leads a program of translational research in ageing and pharmacology at the Kolling Institute of Medical Research. Her research interests include the clinical pharmacology of frailty, optimizing prescribing for older people with dementia, polypharmacy, depr...escribing and the Drug Burden Index, a measure of the functional burden of an older persons medications. She is Chair of the Geriatric Pharmacology Sub-Committee of the Clinical Division of the International Union of Basic and Clinical Pharmacology, Chair of the Editorial Committee of NSW Therapeutics Advisory Group, and serves on the Economic Sub-Committee of the Pharmaceutical Benefits Advisory Committee. Her clinical, research and policy work all aim to optimise medicines for older people. THE GERIATRICIAN'S SALUTE: DE-PRESCRIBING TIPS Optimsing prescribing for older people requires frequent reassessment. Multiple morbidities, multiple medications, impairments of physical and cognitive function and geriatric syndromes may accumulate over time; with impacts on physiology, pharmacology and treatment goals that need to be considered. Deprescribing is the process of withdrawal of an inappropriate medication, supervised by a health care professional with the goal of managing polypharmacy and improving outcomes. This talk will cover assessment of inappropriate medications for older patients and the process of deprescribing. It will examine current issues in practice, research and policy.

15.01.2022 Who better than Henry Brodaty to tell us about Behavioural and Psychological symptoms (BPSD, Neuropsychiatric symptoms, NPS) that occur at some stage in nearly everyone with dementia. The symptoms cause distress to the persons with dementia themselves, to their families, to other residents and to their professional carers. This presentation will cover the multiple causes of BPSD and the evidence for psycho-social and pharmacological strategies illustrated with case vignettes.... Henry Brodaty is Co-Director of Centre for Healthy Brain Ageing, Scientia Professor of Ageing and Mental Health and Director, Dementia Collaborative Research Centre at UNSW. He is a senior psychogeriatrician and Head of the Memory Disorders Clinic at Prince of Wales Hospital in Sydney. He is Immediate Past-President of the International Psychogeriatric Association and a former President of Alzheimers Australia NSW and Alzheimers Australia and Chairman of Alzheimers Disease International. In June 2016 he was the recipient of the Ryman Prize for the worlds best development, advance or achievement that enhances quality of life for older people.

14.01.2022 Registrations for this year's Master Class will be closing soon, so please encourage your colleagues to register ASAP: http://bit.ly/MasterClassBrain2019 Check out the program highlights below... See you there! Simon Bassel Hassan will discuss headaches in older patients, which pose a distinct set of diagnostic challenges including increased risk of sinister underlying causes, atypical presentations and hybrid headache syndromes. Chris Blackwell will tackle the Old Chestnut of Managing Mood and Psychosis in the Older Patient. This talk will provide a practical overview to the difficult choices that underpin this imperfect world where the lack of magic bullets demands significant ongoing considerations for the clinician. Steve Winters will cover the advances in hyperacute stroke care that have revolutionised outcomes for older stroke patients and discuss how stratifying the risk of cerebrovascular disease is essential towards selecting the best preventative therapies. Sue Kurrle will look at where Frailty and the Older Brain Collide. This presentation will look at how these two common conditions overlap and interlink and what the evidence tells us about what we can do to intervene. James Burrell will discuss the classification of non-Alzheimer dementias, introduce the main clinical features through case discussion, discuss current diagnostic criteria, explore the diagnostic utility of neuroimaging and examine clinicopathological correlations. Finally, he will outline an approach to management.

14.01.2022 Check out: Death on the Beach: The First World Conference on End of Life Psychiatry Capacity Australia has brought together a range of experts speakers from around the world in psychiatry, palliative care, geriatrics, intensive care, human rights and law to extend the concept of successful or healthy ageing to Positive Dying... Date: Thursday 1st March 2018 Venue: Horizons, Maroubra Beach TO REGISTER http://capacityaustralia.org.au/death-on-the-beach/ See more

14.01.2022 Registrations for this year's Master Class will close on Thursday, so book now to avoid disappointment. http://bit.ly/MasterClassBrain2019

12.01.2022 Registrations have now opened for Master Class 2017, October 7th and 8th: http://sydney.edu.au/brain-mi/news-events//masterclass.php Please circulate this link to your colleagues. Look forward to seeing you all in October!

11.01.2022 Simon Lewis is an NHMRC-ARC Dementia Fellow who works as a Consultant Neurologist at the Royal Prince Alfred Hospital and is Professor of Cognitive Neuroscience at the University of Sydney. He is the Clinical Director of the Ageing Brain Clinic and Director of the Parkinson's Disease Research Clinic at the Brain & Mind Research Institute and heads the NSW Movement Disorders Brain Donor program. He has published over 140 peer review papers, 2 books and 5 book chapters and ha...s attracted over $5 Million in funding from various sources including the NHMRC, ARC and Michael J Fox Foundation to support his research interests targeting quality of life in neurodegenerative diseases. MANAGING THE UGS & GIT IN THE OLDER PATIENT The elderly patient is prone to issues with both the gastrointestinal tract (GIT) as well as the uritogenitary system (UGS). Many of these can be ascribed simply to ageing but often may be the result or exacerbated by a neurological process. This lecture will focus on the management of common GIT and UGS disturbances that arise in the context of neurodegenerative conditions and some practical steps towards their management.

11.01.2022 Susan Kurrle is a geriatrician at Hornsby Ku-ring-gai Hospital in northern Sydney and at Batemans Bay Hospital in southern NSW. She holds the Curran Chair in Health Care of Older People in the Faculty of Medicine at the University of Sydney. She has had a long interest in the diagnosis and management of dementia, and has developed memory clinics in both urban and rural settings. She leads the NHMRC Partnership Centre on Dealing with Cognitive and Related Functional Decline in... Older People. Managing the physical comorbidities of dementia To date assessment and management of dementia has focused on cognitive and behavioural symptoms and their management, but the physical side has been neglected. Physical comorbidity is extremely common in people with dementia and there are a number of physical conditions such as delirium, falls, incontinence, visual problems, sleep disorders, and seizures, which occur more commonly in people with dementia than in those without dementia. These can lead to excess disability and reduced quality of life for the affected person and their family. This presentation uses a case study based approach to describe these conditions, and gives evidence based recommendations on how to recognise and manage them.

11.01.2022 Registrations have now opened for this year's Master Class 2019. https://sydney.edu.au//masterclass-diseases-of-the-ageing- Please feel free to disseminate through your networks via the shorter link: http://bit.ly/MasterClassBrain2019... I hope that you will agree we have a terrific program and I look forward to seeing you there. Best wishes Simon

10.01.2022 Master Class 2018 is less than 2 weeks away. One of the commonest scenarios we need help with would be how to Manage Dementia in the Nursing Home patient. Listen to Sue Kurrle's insights. Susan Kurrle is a geriatrician at Hornsby Ku-ring-gai Hospital in northern Sydney and at Batemans Bay Hospital in southern NSW. She holds the Curran Chair in Health Care of Older People in the Faculty of Medicine at the University of Sydney. She has had a long interest in the diagnosis and management of dementia, and has developed memory clinics in both urban and rural settings. She leads the NHMRC Partnership Centre on Dealing with Cognitive and Related Functional Decline in Older People.

08.01.2022 'Twas the night before Master Class and we are all getting very excited! 'See' you tomorrow...

06.01.2022 Old Age Psychiatrist, Conjoint Professor UNSW; Clinical Associate Professor Sydney University; President of Capacity Australia; Co-author of the E-text "Capacity and the Law; Chair of the IPA Taskforce on Capacity; Former Professional Member Guardianship Tribunal NSW (now NCAT). THE REALLY TRICKY BITS: DRIVING, CAPACITY, POWER OF ATTORNEY Decisional capacity can be affected at various times and to a various extent by diseases of the ageing brain. This can affect a gamut of decision-making tasks ranging from driving, sexuality and intimate relationships, death and dying, to medications, research participation, financial management and accommodation. This presentation will provide practical guidance for clinicians in dealing with some of these tricky issues that interface with clinical, ethical and human rights responsibilities.

06.01.2022 Under one month until Master Class 2018 and we have a great program including: Dr James Burrell speaking on Epilepsy as well as Muscle and Nerve diseases in the elderly.

06.01.2022 Registrations have been very strong for this year's Master Class but there are still some places left, so please encourage your colleagues to register ASAP: http://bit.ly/MasterClassBrain2019 We have had to make one small change to the program as Carmelle Peisah is not going to be available, however, she has promised to contribute at next year's Master Class! ... I am delighted to report that we have an excellent replacement speaker in Dr Christopher Blackwell who is a Consultant Psychiatrist in General Adult Psychiatry. His lecture will be tackling, That Old Chestnut: Managing Mood and Psychosis in the Older Patient. I hope that you will agree we have a terrific program and I look forward to seeing you there.

06.01.2022 Managing sleep wake disturbances in the elderly Complaints about sleep fragmentation and somnolence are very high in the older patient and a standard approach is required. Aggravating factors should be addressed and treatable causes must be addressed. This involves careful evaluation of the history, examination and medications. The indications for polysomnography and the management strategies will be covered. Dr Dev Banerjee is a sleep clinician and the medical director of... the Woolcock Institute, University of Sydney, Glebe. He graduated from University of Leeds in 1992, before undertaking postgraduate medical training in Birmingham UK. He spent over a year at the Royal Prince Alfred hospital 2013 - 2014 as a Clinical Research Fellow before returning back to Birmingham to head Sleep services there. He completed his MD in Cell Biology and Microbiology in COPD at the University of Birmingham in 2003. He returned back to Sydney in 2013, initially with the St Vincent's hospital and the Woolcock Institute, before moving fully over to the Woolcock Institute and the Brain and Mind Centre to facilitate the development of sleep neurodegenerative services. He has a specialist interest in sleep disorders in neurodegenerative disorders, movement disorders in sleep, as well as other neurological and psychiatric sleep disorders such as narcolepsy, insomnia, restless legs, sleep disorders in depression, Non REM and REM parasomnias, REM Behaviour disorder and hypersomnia. See more

03.01.2022 Last year Lynette Masters gave us the practicalities behind brain scanning. This year, she's going to be tuning us in to pattern recognition... 'Pattern recognition' and its role in diagnosis covering multiple topics including: # How much is too much small vessel ischaemia # Patterns of atrophy seen in neurodegenerative disease (Alzheimer and Frontotemporal Dementia, Parkinsonian conditions) ... # The spine: wear and tear vs the surgical referral # The vagaries of Normal Pressure Hydrocephalus Lynette Masters initially undertook Neurology training at St Vincent's Hospital before training in Radiology. She then went on to sub-specialise in Neuroradiology undertaking a Neurointerventional Fellowship in New York where she remained for several years working as a Consultant Neuroradiologist before returning to Sydney. She now works as a Neuroradiologist with Southern Radiology based at the Brain and Mind Centre.

03.01.2022 Places are filling up for Master Class 2018 and we have a great program including: Carmelle Paisah an Old Age Psychiatrist, Conjoint Professor UNSW; Clinical Associate Professor Sydney University; President of Capacity Australia; Co-author of the E-text "Capacity and the Law; Chair of the IPA Taskforce on Capacity; Former Professional Member Guardianship Tribunal NSW (now NCAT). Carmelle is going to tell us how to look after ourselves given the pressures of the job. Helping yourself to help your patient!

02.01.2022 So we have some major challenges! snpy.tv/2fizOzx