Central Cardiovascular Regulation, The Allen Laboratory at Melb Uni in Parkville, Victoria, Australia | Science

Central Cardiovascular Regulation, The Allen Laboratory at Melb Uni

Locality: Parkville, Victoria, Australia

Address: The University of Melbourne 3010 Parkville, VIC, Australia

Website: http://biomedicalsciences.unimelb.edu.au/sbs-research-groups/physiology/central-cardiovascular-regulation2

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14.01.2022 Chemogenetics: what a novel technique further advanced by our laboratory and the Bathgate and McDougall laboratories. Here they explain how we developed and used Allatostatin to understand brain function and circuitry.

12.01.2022 Happy National Science week! Here is Dr Mariana Del Rosso De Melo performing the working heart brain preparation. Throughout lockdown 1 she was hard at work, learning and perfecting this very difficult technique.

08.01.2022 Please check out Clement Menuet's recent article, published in eLife, on how the preBotzinger region effects blood pressure and breathing. https://elifesciences.org/articles/57288

03.01.2022 The Allen lab recently attended the ANS (Australasian Neuroscience Society) conference in Adelaide, presenting posters and giving oral presentations. They had a great time!

01.01.2022 We are really excited that our development of a novel inhibitory #chemogenetics approach is just out in @CellReports https://www.cell.com/cell-re/fulltext/S2211-1247(20)31128-1 Move aside DREADD's, make way for Allatostatin!! ... Major collaboration between the @BathgateRoss and McDougall labs @TheFlorey and Allen lab @UniMelbMDHS. The work uses viruses to express the chemogenetic molecule, allatostatin, enabling expression in mammalian neurons, to understand the function of a cell group, expressing the chemogenetic receptor AND the likely source of the driving input circuit-based chemogenetics. What is the importance? Circuit-based chemogenetics could be used to interrogate the functional relevance of any neural circuit. This is a substantial advance in chemogenetics and is freely available with plasmids @AddGene