dr_pran_yoganathan | Doctor

dr_pran_yoganathan

Phone: +61 1300 580 239

Add/Update information

Reviews

Tags

• Businesses
• Doctor
• Medical and health

24.01.2022 We need to be more selective, better educated, have access more complete lipid panels including LDL subfraction analysis and a nation of people more aware on what serum lipids are. Myopic focus on LDL alone is not helpful and it could be harmful.

23.01.2022 Whey protein could be the strongest stimulator of muscle protein synthesis. This could prove to be therapeutic to combat the epidemic of elderly with a catabolic muscle state. Whey contains a huge amount of leucine - which is critical for muscle building. #protein #lowcarb #lchf #keto #carnivorediet #ketoweightloss #ketogenic #ketogeniclifestyle #carnivore #heart #cardiology #healthylifestyle #healthyfood #health #healthy #healthyeating #protein #meat #fish #weightloss #paleo #paleolifestyle #vegan #vegetarian #plantbased #food #doctor #medicine #milk #dairy

23.01.2022 These are the two faces of malnourishment. The developed world shows the side of malnourishment which is energy toxicity with a low protein diet. The developing nation reveals protein malnourishment in the absence of energy. Make no mistake all the children depicted above are malnourished. Obesity is no longer a disease of excess in the developed nations - it is strongly correlated with poverty. The deprivation of quality to protein to a human leads to a energy craving which then spirals into an addictive food behaviour. Fit children predicts a promising future. Obese children predict a future of autoimmunity, cancer, heart disease, mental health woes, diabetes (many more).

22.01.2022 Unless you have the activity and muscle quality (as well as youth) - one probably should learn to manage energy. Whilst calorie counting is simplistic - this example is an excellent demonstration of how an athlete like Michael Phelps earns the energy and needs the energy to fuel his glycolytic muscle fibres. Even an elite athlete such as Michael will struggle to do this beyond his youth - it is not sustainable.

21.01.2022 Elegant how the body regulates blood glucose during fasting at a low/steady state. The addition of exogenous hormones such as steroids (stress hormone Cortisol) elevates the blood sugar. This is the common misconception in the nutrition community - that making sugar via gluconeogenesis is stressful for the body. Addition of exogenous cortisol will push up sugar. Exercise will increase cortisol shorterm - does that mean we shouldn’t exercise? The metabolically unhealthy should utilise their own liver to make their sugar instead of ingesting sugar - this is a solution to their metabolic woes. The presence of the newer diabetic agents can interfere with this and this is why a low carb diet or fasting should be exercised with caution when diabetics are on the newer agents - life threatening keto acidosis can occur.

21.01.2022 The FFQ (food frequency questionnaires) do not distinguish between this. Given most of the population consume the pizza as a protein source rather than a steak. One is calorie rich and nutrient poor, the other is calorie poor and nutrient dense. One is more satiety inducing that the other despite being less in calories.

21.01.2022 This point cannot be over emphasised- it is at the crux of many aspects of our health.

21.01.2022 Amazing photo that captures the people of the Andaman Islands. These islands which are under the jurisdiction of India contain the people that originally colonised Asia from Africa. Because of the isolation on these islands - they were not exposed to the genetic blending that occurred with the Neanderthals and Denisovans and have remained unchanged on their islands. Obesity is now rife in some of the more gentrified parts of the Andaman Islands with the introduction of grains.

20.01.2022 It helps you go to the toilet more frequently but doesn’t address all the factors that make up constipation. This does not sound like the panacea for constipation - note this is a meta-analysis

20.01.2022 Here is a summary of why plant proteins are harder for the human digestive to break down into their respective amino acids. There is no doubt they contain amino acids - but can our digestive tract access them? The metabolic fates of amino acids derived from plant and animal proteins are thus different, leading to metabolic differences in peripheral tissues like skeletal muscle. * Different structure of plant versus animal proteins makes them resistant to proteolysis in the ga...strointestinal tract * Plant based sources contain non-starch polysaccharides or fibers that impede the access of enzymes to proteins and induce a decrease in protein digestibility. * The presence of some bioactive compounds named antinutritional factors, such as phytic acid, protease inhibitors, hemagglutinins, glucosinolates, tannins, and gossypol affect the digestibility of plant-based protein sources. * In addition to the extent of protein digestion, a protein’s nutritional value also depends on its rate of digestion in the gastrointestinal tract. Studies working on the kinetics of protein digestion and amino acid absorption have established the concept of ‘slow’ proteins (like casein) and ‘fast’ proteins (like whey). * Plants have lower content of the protein anabolism regulator leucine, which stimulates protein synthesis and inhibits protein degradation. * Moreover, plant-based protein sources are deficient in certain essential amino acids for body needs (e.g., lysine in cereals). When an essential amino acid is limiting, all other amino acids will not be properly used for protein synthesis and thus get deaminated and oxidized and then irreversibly eliminated. * Clinical and animal studies have also shown that amino acids from soy proteins were more degraded to urea than amino acids from casein or whey proteins and, consequently, were less available for protein synthesis in peripheral compartments, including skeletal muscle. Nitrogen losses by deamination or intestinal loss and splanchnic nitrogen retention are higher after the ingestion of plant-based proteins than after the ingestion of animal-based proteins.

20.01.2022 Great article by a Cardiologist dissecting the saturated fat and heart disease hypothesis. A change is coming... https://www.medpagetoday.com/b/skeptical-cardiologist/87385

20.01.2022 Triglycerides - a marker for caloric excess. Isn’t it sad that our pets develop the same illnesses that we do because they eat like us and move like us. Instead of the drug, we should aim to give them nutrient dense foods with an element of caloric restriction and as much exercise as possible.

19.01.2022 It has some benefits with regards to generating SCFA in our colon - but beyond this it is beneficial as a bandaid to a poor diet rich in refined foods.

18.01.2022 The mother of all #intermittentfasting done by Angus Barbieri. In 1965, a 27-year-old man in Scotland, Angus Barbieri, decided he wanted to lose some weight. At the time, he weighed 456 pounds. Under doctors’ supervision, he began fasting and survived for more than a year without food, setting a new world record. He consumed only non-caloric foods such as tea/coffee and some vitamin supplements. This shows the way the body burns fat for fuel. I have no doubt he also broke down significant amount of bone and protein to maintain his blood glucose at a steady range. Whilst prolonged fasts like this are obviously not recommended it shows the power of human fat in allowing sustenance.

18.01.2022 Amazing to see primary care physicians bringing this into the mainstream. Well done to Dr Liz Fraser.

17.01.2022 This is the golden data from @martykendall76 @nutrientoptimiser that shows that overeating fat in an attempt to lose weight is a zero sum game. It will eventually lead to insulin resistance as there is a clear pattern to overeat calories due to it’s lack of satiety. Fat will store as fat (simple) and will eventually create the inflammatory cascade known as metabolic syndrome. Give @martykendall76 a follow this man is is gathering a wealth of data not even seen in high level nutrition academic papers.

16.01.2022 The wisdom in these words is stunningly accurate. The father of medicine Hippocrates essentially is reinforcing the concept understood in biology that - every living organism thrives in the environment that it was evolved in. We currently exist in an environment that no longer suits our biology.

15.01.2022 The gut microbiome is a colossal mystery - end of story - we are no closer to unlocking it’s secret. There are clues to the optimal environment but the answers certainly do not lie in the expensive pre/probiotics or supplements. Anyone claiming to understand the gut microbiome is a red flag for me.

15.01.2022 The ability to rely on my own fat stores without constantly eating was a game changer for my mental acuity. There is no doubt that my own mental clarity is best with a low level of ketosis bought on by exercise or fasting. This takes some weeks to adapt to.

14.01.2022 #Repost @drjamesmuecke with @make_repost Type 2 in reverse. There are now three proven methods for putting type 2 diabetes into remission. And yet it’s not a major goal of Australia’s National Diabetes Strategy. 4,000 limbs are amputated, 100,000 eyes are injected, and 4.5 million hours are spent hooked up to a dialysis machine every year for patients with type 2 diabetes. And 70% will ultimately develop dementia. ... Shouldn’t every patient with type 2 be given an opportunity to put their disease into remission? Or continue as is and wait for their life-destroying complications to arise? #healthylifestyle #healthyeating #diabetes #type2diabetes #publichealth #health #healthyfood #healthyliving #lowsugar #lowcarb #lchf #lowcarbdiet #highhealthyfatlowcarb #weightloss #antiinflammatorydiet #insulinresistance #reversetype2diabetes #ketocomm #intermittentfasting #metabolichealth @ausoftheyear #ausoftheyear @australianoftheyear #australiaday @australiadaysa #australiadaysa #sightforall @sightforall #socialentrepreneurship See more

13.01.2022 The American College of Cardiology now acknowledge that small dense LDL and Triglycerides are the problematic particles for atherogenic disease (heart disease, stroke). We need more doctors at primary care level in #australia and certainly in #cardiology to speak in these terms. A myopic focus on total cholesterol and LDL alone will miss a lot of people that need urgent care and their risk factors addressed.

13.01.2022 How protein leverage looks like objectively depicted in this 2020 study. Energy intake following the egg breakfast was significantly reduced compared with the cereal breakfast (4518 vs. 5283 kJ, p = 0.001). BMI and gender were unrelated to these effects. The sensation of hunger was less after the egg breakfast (p = 0.028 for diet by time interaction) and returned more quickly after the cereal breakfast.

12.01.2022 Schematic of fatty acids - they are classified depending on the degree of saturation or unsaturation in the carbon chain and the length of the carbon chain. Saturated fat is primarily animal fat, mono/poly are primarily from fish and vegetables. Trans fats are industrially produced.

12.01.2022 This is how a high protein nutrient dense diet places you in a caloric deficit causing weight loss. The average Australian man/woman consumes close to 2000-2500 calories per day to maintain their weight. Despite consuming 5 eggs, large salmon and a 250g T-bone steak over the course of a day - a diet such as this creates satiety, nutrient density and places one on an energy restricted diet. If modern day illness is a disease of excess energy then this is the clear solution without losing part of your stomach with bariatric surgery or yo-yo/starvation/juice diets. In addition to the caloric deficit - the body has to expend 25% of energy eaten to break down this protein and assimilate it into the body. There is no need to over eat fat on a diet like this as the protein brings it’s own fat.

11.01.2022 Fasting for 16hrs will allow your body to burn fat - it is a good recipe for insulin sensitivity and weight loss. Yet this is the common reaction observed. Yet in 1965 a man chose to do this for over a year. The pathway to getting healthy is sometimes a road outside one’s comfort zone.

11.01.2022 All that fuel and we never get to tap into it, because the diet experts tell us we need sugar to run the body.

11.01.2022 The definition of diabetes is literally the inability to clear ingested glucose or sugar from the blood. This is why it is better to force your body to make it’s own glycogen from protein (60% converts to glucose) rather than ingest sugar. It is a well regulated pathway (gluconeogenesis) and not stressful for the body as some claim.

10.01.2022 Nutrition is critical for the doctors in our healthcare industry to understand and master. It made us what we are and additionally it is at the root of modern illness.

08.01.2022 Working muscles consume a mixture of metabolic substrates, and the relative contributions of fat and carbohydrate to this mixture dynamically depend on exercise intensity and the size of available glycogen reservoirs: Carbohydrates account for a greater proportion at higher intensities, while fat accounts for a greater proportion as available glycogen is depleted.

07.01.2022 Fructose has little to no insulin response. The mechanism of damage via fructose in metabolic syndrome is via a different pathway.

07.01.2022 Serotonin as an important modulator of maladaptive behaviors. In men, for instance, low concentrations of this neurotransmitter are related to hostile aggression. A key player in serotonin metabolism seems to be central cholesterol. It plays a fundamental role in maintaining the soundness of neuron membranes, especially in the exocytosis transport of serotonin vesicles into the synaptic cleft. In this review, they explore an evolutionary approach to the neurobiological basis ...of human male violence. Hominid evolution was shaped by periods of starvation but also by energy demands of an increasingly complex brain. A lack of food resources reduces uptake of glucose and results in a decreased energy-supply for autonomous brain cholesterol synthesis. Consequently, concentrations of neuromembrane cholesterol decrease, which lead to a failure of the presynaptic re-uptake mechanism of serotonin and ultimately to low central serotonin. The authors propose that starvation might have affected the larger male brains earlier than those of females. Furthermore, this neurophysiological process diminished the threshold for hostile aggression, which in effect represented a prerequisite for being a successful hunter or scavenger. See more

07.01.2022 This Obsessive focus by cardiologists on lowering cholesterol as low as it can be (especially LDL) is concerning. Especially when it increases the risk of hemorrhagic stroke by 2.17 times in women. The implementation of the potent PCSK9 inhibitors needs to be carefully watched for longterm issues. I believe the medical industry has missed the point with regards to lipid medicine - there is more to it than most doctors understand. We need to empower the people to question their doctors - there is very little in these modern chronic illnesses that can’t be fixed completely by modifying lifestyle.

06.01.2022 Probably the single greatest hypothesis in nutrition. Unfortunately the majority of my colleagues do not think so. We have a lot to fix in the healthcare sector. But I am hopeful that influential doctors such as @drjamesmuecke the Australian of the year will make this country a leader in calling out the food industry and broken nutritional guidelines. Could not be happier that the Australian of the year is leading the way for us with the reality that sugar is a driver of disease.

05.01.2022 Brilliant interview by @shawnbaker1967 with the Don of protein Prof. Don Layman. This is worth a listen. #protein #health #nutrition

04.01.2022 Heart disease is synonymous with cholesterol - however the cholesterol is there as a result of the body’s attempt to heal oxidative stress. What causes the oxidative stress is the real question.

04.01.2022 These are the 4 main barriers that doctors that embrace a lifestyle change for addressing disease face. They are enormous barriers that need to be overcome with the patient themselves and then the other doctors involved in their care. I look forward to the day where all doctors and dieticians are on the same page. Very proud to work with dieticians at the Centre For Gastrointestinal Health in @jessicaturton_dietitian and @tompaavola_dietitian to deliver a consistent message for our clients

04.01.2022 Serotonin + Dopamine are vital neurotransmitters that we require. Look at the diagram closely to see how nutrition will affect their production. Faced with a mental health epidemic - we need to prioritise nutritional psychiatry.

03.01.2022 The popular misconception is that iron in plants is readily bioavailable to the human gut - this is incorrect. In addition to this, when the iron is bound to globulin (protein) there is far better absorption due to something that is termed the meat factor.

03.01.2022 Amazing images from the great @sebastiao.salgado.photographs capturing The Yanomami: An isolated yet imperiled Amazon tribe. These hunter gatherers live an ancestral mode of life deep in the Amazon. Study of these groups can often allow us insight into the life we evolved to live in stark contrast to modern living.

02.01.2022 In addition to a lack of digestibility of plant based protein is lower in the essential amino acids. In addition to the PDCAAS, the FAO Expert Consultation on Dietary Protein Quality Evaluation in Human Nutrition suggested that proteins should be described based on their digestible amino acid content. Each amino acid should be considered as an individual nutrient, since digestibility may differ among amino acids.