Macquarie University Neuroinflammation Research Group in Sydney, Australia | Medical and health

Macquarie University Neuroinflammation Research Group

Locality: Sydney, Australia

Address: 2 technology place 2109 Sydney, NSW, Australia

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25.01.2022 Great work on breast cancer from Dr Benjamin Heng published today: https://link.springer.com/epdf/10.1186/s13058-020-01351-1

24.01.2022 https://m.youtube.com/watch?feature=youtu.be&v=pWZuvwwZX_A

23.01.2022 Vale Dr Neil Spector, humanity has lost a noble soul today. Neil contributed so much to clinical research into cancer and tick borne disease including scientifi...c collaboration with PANDIS. Neil achieved so much despite his own courageous health battles including a harrowing heart transplant. Prof Gilles Guillemin had the pleasure to meet with Neil in the USA earlier this year after years of memorable zooms and PM's. I include the photo of Neil (left side of pic) and Gilles below. On behalf of the PANDIS consortium we honour Neil's significant research legacy and will continue to incorporate his findings into our work. Our sincere condolences to Neil's wife and daughter and to those whose lives he selflessly and indelibly touched. I include a tribute to Neil written by Dana Parish below, they reflect our sentiments too. The world has lost a hero and Heaven has gained an angel. It is with the heaviest heart that I share with you that our beloved Dr. Neil Spector passed away last night after a ferocious battle that began with a long-undiagnosed case of Lyme, which led to a heart transplant and subsequent remarkable comeback. Neil meant so much to the world, to all of us, and we meant so much to him. Nothing lit him up more than his beautiful family-- his wife Denise, daughter Celeste, and sweet pup Turbo. He loved his friends, his patients, his colleagues, the Lyme and cancer communities who he gave his soul to, and his life's work as an oncologist and scientist, which was filled with marvelous, life-saving cancer discoveries, and as of late, he made huge strides in the field of tick-borne diseases. He also loved a good gluten-free pizza with a glass of merlot and a spirited discussion about music, medicine, politics, travel, his dreams of another island get-away with Denise and Celeste. Neil was a poet, a memoirist, a marathon runner, the most gorgeous, generous, soulful, gem. He was gentle, humble, fierce, brilliant, the most caring, compassionate, intuitive, selfless human on Earth. He was a straight-shooter who suffered no fools when it came to scientific integrity. Neil belonged to the truth. I would jokingly pinch him to make sure he was real. My mom called him a sugar plum. When she had breast cancer a few years ago and went through chemo, he Facetimed her each week, like clockwork, on his own volition, to cheer her on. She would not have gone through with her life-saving treatment, she said, had he not pushed her (with 5 phone calls!) to do so. Her own oncologist was in disbelief as she had no luck in convincing my mom to go through with it. He will forever be missed, he will forever be loved, he will forever be ingrained in our hearts. And if there's one thing I know for sure, he will be the wind on our faces, the birds that sing in our windows, the feathers that fall at our feet. I love you so much, Neil, my dear soulmate, brother, angel. Thank you for your love and devotion. Thank you for giving everything you had to the world. You are the gift that will never be replaced.

22.01.2022 Congratulations to Dr Sundaram for her study demonstrating that "Kynurenine Pathway Modulation Reverses the EAE Mouse Disease Progression". Huge therapeutic potential! https://pubmed.ncbi.nlm.nih.gov/32505212/

22.01.2022 https://www.ncbi.nlm.nih.gov/pubmed/32074550/

22.01.2022 Article en francais / sorry article in French... https://www.lecourrieraustralien.com/covid-19-questionsa-/ #pandis #coronavirus #MyMq #LighthouseNewsflash

21.01.2022 https://m.facebook.com/story.php?story_fbid=721036415278361&id=329330804448926

21.01.2022 This article is link with our project on cyanotoxins and brain diseases: https://www.canberratimes.com.au//climate-change-could-b/

21.01.2022 https://www.technologynetworks.com//analyzing-blood-metabo

21.01.2022 Congratulations to our PhD student Ananda Staats Pires for this excellent review on the cross interactions between the kynurenine and BH4 pathways in pain. https://www.frontiersin.org//10.3389/fnins.2020.00620/full

20.01.2022 Back to my original training = Virology! https://www.scimex.org//expert-reaction-tigers,-cats-and-d

20.01.2022 https://www.mq.edu.au//18/10-questions-with-benjamin-heng/

19.01.2022 Amazing work from my collaborator and friend Lena Brundin: https://www.facebook.com/553129871/posts/10157760643519872/

18.01.2022 2020 ISTRY MEETING WILL BE IN GERMANY IN SEPTEMBER https://www.uniklinikum-jena.de/istr//Welcome+Message.html

18.01.2022 Thank you Trudy Scott Antianxiety Food Solution for the book. Very interesting, highly recommended. Kind regards Prof Gilles Guillemin PANDIS

18.01.2022 https://phys.org//2019-10-lakes-worldwide-experiencing-sev

18.01.2022 https://www.technologynetworks.com//flame-retardants-and-p

18.01.2022 https://www.facebook.com/youngtryptophanresearchers/

17.01.2022 Just found this message on my LinkedIn, amazing compliment ! thank you so much to A.S. MD (CA, USA) for these very kind words

17.01.2022 https://www.lecourrieraustralien.com/covid-19-questionsa-/

16.01.2022 Let us introduce you to Dr. Vanessa Tan, Research Fellow from the Neuroinflammation and Neurotoxicity Group. Working as a research assistant, Vanessa was part ...of the first cohort of researchers that started at the Centre in 2013, where she first began her learning journey about this devastating disease. Vanessa then committed to dedicate her scientific career to fighting MND from the laboratory, I felt that science knew too little about MND, its causes and the factors that affect it she says. Vanessa is currently investigating biomarkers (measurable biological characteristics such as proteins found in blood) that can help us to determine different disease subtypes of MND and give a clear indication of the rate of disease progression, in the hopes that biomarkers will allow clinicians to have a consistent and more reliable way to measure disease progression. She is also studying the role of environmental factors in MND, such as a neurotoxin named BMAA, which is present in algae commonly found in water sources world-wide. She is working to determine if BMAA contributes to the cause of MND, and the potential mechanisms behind how BMAA causes toxicity that can lead to MND. Vanessa has not only battled MND from the lab bench. She was also involved in establishing the Neurodegenerative Disease Biobank and has had the amazing opportunity to work with patients from Macquarie’s MND Clinic: The clinic and biobank have always been a soft spot for me, as meeting the patients, and chatting to them about our research at the Centre is how it reminds me that our work is important, and how we can make a difference! When not working in the lab or the clinic, Vanessa loves baking. It is her very own lab at home. The most popular requests are her chocolate tart and the carrot cake, even though she’s not a big fan of the latter: I don’t like carrot cake, but everyone else does!. Well, definitely count us in for a slice of carrot cake! Vanessa is determined to make a significant contribution to our knowledge of the disease: The understanding of MND is really behind times, and we should really know more about it!. We know you’re making a big difference Vanessa! You can find out more about Dr. Tan’s work at: https://researchers.mq.edu.au/en/persons/vanessa-tan-2

14.01.2022 Our latest collaborative paper reporting the identification of the transporter for the neurotoxin quinolinic acid that is found elevated in most of brain diseases, MND, Alzheimer, MS, Parkinson, COVID19, etc... Macquarie University PANDIS Alzheimer's Association @DSCATT MStranslate Fight MND UNSW The University of Queensland Kissgoodbyetoms

14.01.2022 Congratulations to our collaborator Dr Lena Brundin

13.01.2022 Congratulation to Dr Gayathri Sundaram for this study demonstrating that by blocking enzymes of the kynurenine pathway, she was able to stop MS in an EAE mice model. Huge therapeutic potential! https://pubmed.ncbi.nlm.nih.gov/32505212/

13.01.2022 Thanks to my team for celebrating my birthday today! Special thank to Sharron for the tiramisu xxx

12.01.2022 Result of a collaborative project with USA scientists

12.01.2022 Our latest publication on biomarker for ALS through a collaboration with USA. We found that 2 molecules related to muscles (creatine and creatinine) are the most relevant markers (ALS vs Controls) Also not surprisingly we didn't detect BMAA in the blood of ALS patient. The cyanotoxin is not circulating abut hides somewhere in the body... Liver may be? or is integrated in proteins?... https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00216#

11.01.2022 Another very successful year for the Neuroinflammation group, more than 30 papers published in 2020! We all deserved a nice Xmas party celebration with the whole team Macquarie University

11.01.2022 https://www.bbc.com/news/world-africa-54234396

11.01.2022 Cooked to much chicken couscous last night, so brought some to Macquarie University for lunch today and shared with my 2 senior scientists, Ben & Charlie, and Sharron & Ananda.

11.01.2022 Our latest review paper on gut microbiome, kynurenine pathway and brain cancers BrainCancer.org Cure Brain Cancer Glioblastoma Foundation Viome Kynurenine https://www.frontiersin.org//10.3389/fcell.2020.562812/full

09.01.2022 Tryptophan & turkey. Don't blame these poor birds for your sleepiness - see Lena Brundin's post: https://www.vai.org/dont-blame-tryptophan/

08.01.2022 NEXT ISTRY MEETING IN GERMANY IN SEPTEMBER 2020 (please share !) https://www.uniklinikum-jena.de/istr//Welcome+Message.html

08.01.2022 After a tough week, the NIF group is having a beer and pizza evening at Ubar

08.01.2022 Time to do the same for Australia!

07.01.2022 our first virtual lab meeting!

07.01.2022 Our work on MS! https://youtu.be/jcARtUJL1CE

07.01.2022 Macquarie University researchers have been awarded $14 million in funding for health research projects including Alzheimers Disease and Motor Neurone Disease (...MND). The picture shows, from L-to-R, Professor Gilles Guillemin and Professor Ian Blair from Macquarie Universitys Centre for MND Research. https://www.miragenews.com/macquarie-university-wins-14-m/

06.01.2022 Again, Well done to Dr Benjamin Heng! https://t.co/N1Lvndo5VT Thank you to #FightontheBeach & TourdeCure for funding this project! ... #macquarieuniversity #BCNAPinkLady #BreastCancerAwarenessMonth #breastcancerawareness Loveyoursistersss

05.01.2022 "Tryptophan and its metabolites including melatonin have the capacity to improve the immune system and reduce inflammation in various conditions. Here, we discu...ss the potential of using tryptophan and its metabolites including melatonin to boost the immune system in fighting COVID-19 infection" It's exciting to see this paper published by Sydney researcher and neuroscientist Professor Gilles Guillemin. I just had the pleasure of "meeting" him via zoom and I am so impressed by all his research on tryptophan. I can't wait to meet him in person! The paper - Possible role of tryptophan and melatonin in COVID-19 https://journals.sagepub.com/doi/10.1177/1178646920951832 More on PANDIS here ....‘Environmental health and medical research platform, investigating pathogenic microbes in chronic disease and cancer’ https://pandis.org/ I talk about this paper on the upcoming summit ... and how both serotonin and GABA support is important for immune function, fighting all infections, easing anxiety and improving sleep. Register for The Anxiety Summit 6: Toxins, Meds & Infections, Nov 2-8, 2020, here https://theanxietysummit6.com/?idev_id=739

03.01.2022 our latest paper on kynurenine pathway and osteoporosis. https://asbmr.onlinelibrary.wiley.com//a/10.1002/jbmr.4125

03.01.2022 https://m.medicalxpress.com//2019-10-anti-inflammatory-age

02.01.2022 Very happy to have Dr Richard Schloeffel joining the team at MQU today as Senior Clinical Lecturer. Welcome on board Richard! Richard Schloeffel

02.01.2022 listen to this and don't be a COVIDiot.... SARS-COV2 is a really nasty virus...

01.01.2022 https://www.technologynetworks.com//personalized-medicine-

01.01.2022 We are delighted to announce Anthony Field has been made an ambassador of PANDIS. Affectionately known as the "blue" Wiggle, Anthony has written a book 'How I G...ot My Wiggle Back: A Memoir of Healing' his inspiring, behindthescenes story of how he overcame depression, life-threatening illness, and chronic pain to get his life back. Prof Guillemin and Anthony (pictured) indelibly bonded over their determination to significantly improve outcomes for vector-borne disease patients in Australia - two great men who are a force to be reckoned with! See more