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24.01.2022 Sleep loss caused a 20% decrease in insulin sensitivity and changes in the gut microbiome in a small pilot trial in humans. The decreased insulin sensitivity wa...s, however, unrelated to alterations in gut microbiota following sleep loss. The study involved restricting sleep to ~4 hours per night for two consecutive days. The sleep loss caused a composition change in the gut microbiome including an increased ratio of Firmicutes to Bacteroidetes (which parallel the gut microbiome of obese subjects compared with normal-weight subjects).
24.01.2022 TRIPLE the amount of sulforaphane in your broccoli sprouts with this one Weird Trick! In todays video, I show you guys how to get more biologically active sulf...oraphane out of your broccoli or broccoli sprouts. This is important because sulforaphane is a powerful compound functioning both as a cancer preventative and all around super molecule. See more
23.01.2022 Infants (1-month old) with low levels of four types of commensal gut bacteria had a 3-fold higher risk of allergies by the age 2. Many of these children develop...ed asthma by the age of 4. The allergy-prone children lacked anti-inflammatory polyunsaturated fatty acids and breast milkderived oligosaccharides which caused an increase in inflammatory-producing immune cells and a decrease in immune cells that prevent autoimmune responses. Future studies will try and identify the exact causes of such disruptions in the infant microbiome including breastfeeding and mode of delivery.
21.01.2022 What if chronic activation of your immune system actually shortened your life? Chronic, low-level activation of inflammation accelerated aging and shortened lif...espan by 30% in mice, suggesting that chronic enhancement of pro-inflammatory mediators really is not just a bystander but an actual driver of aging. These data are in line with a recent study in exceptionally old populations (from 90-110+ years old) that identified low inflammation was the only predictor of survival and cognitive function (aside from age itself). In my opinion, this implies that we should try and attempt to mitigate inflammation in order to live a long and healthy life.
21.01.2022 Hey, it's just a soda... what can it hurt? Study shows the habit of drinking sugar sweetened beverages, equal to one can of soda per day, increases the likeliho...od of developing pre-diabetes by 46% over a 14-year period! Higher sugar-sweetened beverage intake, perhaps unsurprisingly, was also associated with increased insulin resistance.
21.01.2022 Lack of physical activity is associated with a 28-59% increased likelihood of early death compared to active folks. This study, which included data from more th...an one million men and women, found that 60 to 75 minutes of daily moderate intensity exercise eliminated the increased risk of early death associated with sitting for over eight hours per day. See more
20.01.2022 A compound found in pomegranate improves muscle function and endurance by 42% in mice and increased lifespan by more than 45% in worms. The pomegranate compound... is transformed by gut microbes into a molecule called urolithin A which causes cells to clear away damaged mitochondria and recycle their defective components for energy. See more
19.01.2022 Raw garlic may have a profound effect on lowering risk factors for cardiovascular disease, which is the #1 cause of death in the U.S. 20 grams of raw garlic an...d 1 tablespoon of lemon juice for eight weeks lowered triglycerides by ~22%, LDL cholesterol by ~24%, and fibrinogen by ~40% in a trial of people with hyperlipidemia (high blood lipids). See more
19.01.2022 People that consistently run even just 50 minutes per week have a 30% lower all-cause mortality and a 50% lower heart disease related mortality compared to non-...runners. The question still remains whether there is an "optimal" running dose... and even if it does exist, it may vary from person to person. Other studies have found that even extremely high levels of running (40 miles per week) have been linked to a 26% lower risk of coronary heart disease when compared to someone that runs "only" 13 miles per week.
18.01.2022 The science of gut health could radically change modern medicine! Within one year, youll be able to have the bacteria that live in your digestive tract analyzed. Within 10, your grocery list could be tailored to those results. Chances are you dont routinely think about the forces roiling in your gut. But all too often, theres a complicated turf war being waged in there think of it as an intestinal Game of Thrones.... You might have strange, hard-to-diagnose symptoms of feeling subpar, like bloating, cramps or a persistent brain fog. Or maybe you get every cold that comes around, have chronic sinus infections or suffer from an autoimmune disorder. Power-hungry microbes are likely to blame. The typical North American gut is home to some 100 trillion representatives of anywhere from 300 to 1,200 different species of bacteria all vying for real estate. When they work in harmony, these microbes build peaceful kingdoms. In return for their room and board, they happily coax nutrients out of dietary fibre, make vitamins, produce hormones, fend off disease-causing pathogens, regulate our metabolism and fine-tune our immune system. They even influence our moods and affect our behaviour. As Erica Sonnenburg writes in The Good Gut, These bacteria are paramount to our health and well-being. Each species has its own predilections, food preferences and appetites. If they dont get what they want, it can get pretty nasty. Without the food they need, the starving microbes turn on us. And that has implications for the development of inflammatory bowel disease, type 2 diabetes, obesity, eczema, asthma, autism, Alzheimers and Parkinsons. Basically, when things go wrong in the gut microbiota, something goes wrong with us. Although scientists have been studying the microbiota for years, DNA sequencing technology has rapidly accelerated their research. Every month, another study comes out with startling discoveries about this microscopic universe: how four key bacteria species can ward off the development of asthma in infants, how a microbial imbalance can lead to celiac disease, how certain microbes affect rheumatoid arthritis and so on. Much of this research indicates that these microbial communities are a major factor in the skyrocketing rates of allergies, autoimmune disorders and obesity. As Sonnenburg, a senior research scientist at the Stanford University School of Medicine, says, I think theres something fundamental about our microbiota thats making us sick.
18.01.2022 Its Rocktober and what a way to start. Tait Fletcher is a pirate, entrepreneur, black belt, actor, stuntman and philosopher. With a very colourful yet dark ba...ckground, this former UFC MMA fighter now runs Caveman Coffee Co, he owns nightclubs, is a stuntman in Hollywood acting with Denzel, Arnie, Mark Walburg, The Rock, & others, and also hosts Pirate Life Radio a successful podcast show. But its Tait straight up approach to life, success, beating the odds and his desire to be of service in order to help others that has you captivated. One of our best shows ever, you will want to hear this one over and over as Tait drops some serious truth bombs on the Mojo Radio Show. See more
16.01.2022 Who are you? Are you one self or a million different selves? Are you the same self when you are exhausted as when you are energized? Are you the same self when ...you are emotional as when you are tranquil? Are you the same self as yesterday? A year ago? One of my favorite quotes from Heraclitus reads, "No one ever steps into the same river twice, for it is not the same river and not the same person." We are always changing and evolving. The past does not define you. You are whomever you are today. Forgive the past, clean the slate, pardon the transgressions so you can be your best self right now.
16.01.2022 Omega-3 fatty acid DHA reduces stroke-like brain damage and protects brain mitochondria in animals. The study involved 10-day old mice that were given brain da...mage that decreased blood flow and oxygen to the brain. Those animals that were injected with DHA were protected from damage largely due to the fact that DHA accumulated in the mitochondria and prevented oxidative stress that normally occurs after blood flow is restored to the brain. See more
16.01.2022 Mechanism explaining the anti-depressant effects of exercise? Endurance exercise in humans prevented the formation of a neurotoxin (quinolinic acid) that is ass...ociated with depression by increasing enzymes in skeletal muscle that convert the precursor into another metabolite that is not harmful. See more
16.01.2022 Hey, its just a soda... what can it hurt? Study shows the habit of drinking sugar sweetened beverages, equal to one can of soda per day, increases the likeliho...od of developing pre-diabetes by 46% over a 14-year period! Higher sugar-sweetened beverage intake, perhaps unsurprisingly, was also associated with increased insulin resistance.
15.01.2022 Check out our Instagram page to stay up to date with all our "New" Product Releases, Exclusive Product Specials, Blogs & Media Posts. https://www.instagram.com/mydfx/
13.01.2022 A double-blind, placebo-controlled study found that supplementation of omega-3 fatty acids & gamma-linolenic acid improved reading skills in 9-year old schoolch...ildren. The study included 154 third-grade schoolchildren from Sweden & those that took the omega-3 supplements (558 mg EPA, 174 mg DHA) and gamma-linolenic acid (60 mg) did better than those taking the placebo on a computer-based test that measured their reading skills in a variety of ways, including reading speed, ability to read nonsense words and vocabulary.
13.01.2022 Book readers that read 30 minutes a day had a 20% lower all-cause mortality over non-readers regardless of health, wealth, or education. The analysis suggested ...that the survival advantage was due to the effect that book reading had on cognition since cognitive capability at the start of the study had no effect on survival over the 12-year follow-up. See more
13.01.2022 The best version of YOU is always in front of us - not behind us. Double Tap & share if you agree. Comment below with your favorite workout ideas. #LiveOptimal ...#naturalstacks #fit #fitness #health #healthyliving #workout #biohacking #crossfit #bodybuilding #weightlifting #bodyweight #outdoors #nature #gym See more
11.01.2022 People that took curcumin (500 mg/d) for 2 months alleviated symptoms of nasal congestion, sneezing & rhinorrhea through reduction of nasal airflow resistance. ...There was no effect in the placebo group. Curcumin was found to affect the inflammatory response in the nasal mucosa by significantly reducing the proinflammatory cytokines, IL-4 and TNF-, and significantly increasing the anti-inflammatory cytokine, IL-10.
11.01.2022 Watch that pumpkin spice latte! Men experienced a 25% decrease in testosterone for up to 2 hrs after 75g of sugar intake. The study included men (19-74 years) with varying glucose sensitivities ranging from normal to type 2 diabetes.
11.01.2022 Supplemental probiotics for 12 weeks moderately improved cognition in Alzheimer's patients and also lowered inflammatory markers, triglycerides, VLDL, and marke...rs of insulin resistance. There was no cognitive improvement in the placebo group. The participants took 400 billion Bifidobacterium bacteria per day, which is a larger amount than you would find in *most* (but not all) commercial probiotics. It is likely that the probiotics are working through multiple mechanisms such as lowering inflammation and increasing neurotransmitters. Other studies have shown that gut bacteria are able to modulate the levels of GABA, norepinephrine, serotonin, dopamine, and acetylcholine through the gut-brain axis. I spoke with the gut experts, Drs. Justin and Erica Sonnenburg, about the importance of the gut microbiome in human health and the various foods (ie. fermentable fiber and other prebiotics) that provide our gut bacteria with the food they need to thrive. Here is the interview (also available on iTunes and Stitcher): https://www.youtube.com/watch?v=gOZcbNw7sng
10.01.2022 In a study of 70,495 people, those supplementing with fish oil, eating fish or both had an 18% lower all-cause mortality and a 23% decrease in cancer death. An...other study published a few months ago found that for 1% increment in omega-3 fatty acids (from both food and supplemental sources) in blood was associated with a 20% decreased risk in all-cause mortality. Yes, I still take fish oil. One important factor often overlooked in studies is whether the fish oil source is oxidized (ie. rancid) or not.
10.01.2022 Cancer patients that fasted for up to 72 hours before treatment with a common chemotherapy drug, had lower DNA damage in their normal immune cells which transla...ted to fewer patients having toxic side effects on the immune system including myelosuppression (a serious side effect of chemo where there is a decrease in blood cells). Coming soon! I recently interviewed a senior author of this paper, Dr. Valter Longo. In this podcast we discuss this study and many other studies he has published on fasting, cancer, and aging.
08.01.2022 Premenopausal women in the highest third of vitamin D levels (>30 ng/ml) were 48% more likely to remain cancer-free during the 7-year follow-up. Additionally, w...omen of all ages in the highest third of vitamin D levels had a 30% better survival rate than women with the lowest vitamin D levels. While this data is very interesting and in line with many other associative studies... to definitively prove that the link that vitamin D and breast cancer survival is causal, randomized clinical trials vitamin D supplementation vs placebo would be necessary.
08.01.2022 Dopamine levels decrease in the brains of people that were injected with a proinflammatory cytokine (interferon gamma) but not placebo. The decreased dopamine l...evels were also accompanied by a reduction in the activation of the reward circuitry. These data reveal that systemic inflammation can affect neurotransmitter levels and function in the brain and highlight the importance that lowering chronic inflammation may have in overall brain function and behavior.
08.01.2022 Australian visit with the guys Lacie, Tait and Keith @ Caveman HQ.
08.01.2022 Have to say we loved interviewing @ryanmunsey from @naturalstacks for #rocktober on @themojoradioshowpodcast about the upgrading of the software and hardware of... our brains to get the most out of our day and our lives. Learn about nootropic and smart drug #ciltep and how it can improve your focus and memory. We are trying it and we reckon it is amazing. http://bit.ly/2dLn4gP See more
07.01.2022 Skin cells were successfully converted into brain cells using CRISPR gene editing technology in mice to specifically activate 3 master genes that control whethe...r a cell will become a neuron. Studies on human cells are next. The significance of being able to turn a skin cell into a neuron is the potential replacement of damaged or dead neurons found in neurodegenerative disorders and other brain injuries. See more
06.01.2022 Spice up your life with turmeric. David Wolfe explains 6 reasons why daily consumption of turmeric is more than just a food flavoring.
06.01.2022 New research finds the gut microbiome communicates with cells of its host organism to switch genes on and off via epigenetics. The research was done in mice an...d found that fermentation of plant fiber results in the production of short-chain fatty acids, which are partially responsible for communicating with the epigenome. See more
06.01.2022 Low in sugar, packed with gluten free, non-GMO ingredients, and delicious!
06.01.2022 Another reason to be physically active? Exercise induces the release of a hormone called irisin, which burns fat by increasing mitochondrial number in fat (browning fat), induces stem cells to differentiate and form bone and suppresses arterial plaque formation.
05.01.2022 Epic smores happening at the first night of Outessa Summit Powder Mountain. Capping off a rad day of womens climbing, mountain biking, backpacking, and outdoo...r clinics. #sweatydirtyhappy #purenaturalenergy #womeninthewild #getoutside #outessasummit See more
05.01.2022 Healthy men that performed 20-40 minutes of aerobic exercise (cycling) experienced a 32% increase in serum brain-derived neurotropic factor (BDNF). BDNF robustl...y increases the growth of new neurons in the brain and in the muscle it plays a role in repairing damaged muscle. This study also found that more intense and longer duration (40 min.) aerobic exercise increased the probability of an individual subject achieving a significant BDNF increase and in the integral (i.e. the volume of circulating BDNF).
05.01.2022 Milk from Tasmanian devils contain peptides that appear to kill antibiotic-resistant bacteria such as MRSA. The antimicrobial compounds are called cathelicidins... and have been shown to kill MRSA, Vancomycin-resistant enterococcus, as well as fungi, called Candida. Scientists believe devils evolved these peptides to help their young grow stronger and allow them to thrive in a relatively dirty environment.
04.01.2022 Overweight & obese people had brain atrophy in white matter brain region equal to 10 years of brain aging compared to lean individuals. The good news is that t...here is overwhelming evidence that exercise greatly increases neurogenesis in the hippocampus. Another study published this week found that rats that ran an average of 9 miles per week for a month had doubled the number of neurons in the hippocampus, the part of the brain responsible for learning and memory. See more
03.01.2022 Approximately 75% of antibacterial soaps have triclosan, which has been linked to tumor growth, allergies, hormone disruption, drug-resistant bacteria and more ... and soon it will be banned. Triclosan has been found in the urine of about three-fourths of doctors and nurses. It is also among the most common chemicals to be detected in streams.
03.01.2022 Supplemental probiotics for 12 weeks moderately improved cognition in Alzheimers patients and also lowered inflammatory markers, triglycerides, VLDL, and marke...rs of insulin resistance. There was no cognitive improvement in the placebo group. The participants took 400 billion Bifidobacterium bacteria per day, which is a larger amount than you would find in *most* (but not all) commercial probiotics. It is likely that the probiotics are working through multiple mechanisms such as lowering inflammation and increasing neurotransmitters. Other studies have shown that gut bacteria are able to modulate the levels of GABA, norepinephrine, serotonin, dopamine, and acetylcholine through the gut-brain axis. I spoke with the gut experts, Drs. Justin and Erica Sonnenburg, about the importance of the gut microbiome in human health and the various foods (ie. fermentable fiber and other prebiotics) that provide our gut bacteria with the food they need to thrive. Here is the interview (also available on iTunes and Stitcher): https://www.youtube.com/watch?v=gOZcbNw7sng
02.01.2022 CRISPR human genome editing gets clear from NIH. Cancer patients will have immune cells edited to target and kill cancer cells. The aim of this clinical trial is to investigate the safety of CRISPR technology in humans and not whether the genome-editing effectively kills cancer cells.
01.01.2022 Human intelligence may have more to do with blood flow than sheer size. Study finds that the human skull remodeled to accommodate only a 350% in size while dema...nd for actual blood flow went up 600% over the course of evolution. The increased blood flow would bring oxygen, glucose, and other nutrients to meet the high metabolic requirements of the human brain.
