Tréidlia Biovet, Mark White BVSc PhD in Seven Hills, New South Wales | Biotechnology company

Tréidlia Biovet, Mark White BVSc PhD

Locality: Seven Hills, New South Wales

Phone: +61 2 9674 1488

Address: Unit 76/45 Powers Road 2147 Seven Hills, NSW, Australia

Website: http://www.treidlia.com.au

Likes: 640

Add/Update information

Reviews

Tags

• Biotechnology company

24.01.2022 FOWL POX SEASON IS HERE Owners of heritage and hobby poultry in Fowl Pox prone parts of the country should be thinking about vaccinating their birds soon. Fowl Pox is a viral disease of chickens which is spread by biting insects like mosquitoes. Once established in a flock it can spread from bird to bird. It usually starts off with a few birds showing swellings, lumps and scabs on the featherless parts of the skin... comb, wattles, legs, near eyes, near beak. Less commonly it... can form inside the mouth. Its more common in areas with warm, moist summers and autumns. It can be a bigger problem in wetter years. In individual birds it can last up to a few weeks and in flocks up to a few months. Most birds with lesions only on the skin eventually recover, but it can play havoc with show and sale plans. Individuals with lesions near the eye or beak, and especially those with internal lesions in the mouth, often develop complications and may not do well long term. Flocks with Fowl Pox sometimes seem to develop other disease problems. There is no real treatment. Iodine and other wound dressings are used but essentially the disease runs its course. Vaccination is the main control measure. Its a live vaccine which needs to be stored in the freezer. It is given by dipping a prong into the reconstituted vaccine then poking that into the skin of the wing web. In small scale flocks birds are usually vaccinated between 4-12 weeks of age. For optimum protection, especially in high risk areas, a second dose should be given 4-8 weeks later. Another option, since there tends to be leftover doses available anyway, is to vaccinate all the chicks and all the adults (or at least all the younger adults) at the same time once a year. Doing it like this helps cover any deficiencies in vaccination technique and prevents decline in immunity in hobby breeding stock, which tend to live longer than commercial stock. The vaccine takes about 2 weeks to work. Its possible to check if it was given properly by checking the inoculation site 7-10 days afterwards, at which time there should be a "take" or swelling should be visible in most birds. Turkeys and pigeons get similar diseases. For turkeys use the Fowl Pox vaccine. For pigeons use the separate Pigeon Pox vaccine.

22.01.2022 Update on Calicivirus in Rabbits The new Calicivirus strain (RHVD2) continues to plough a path of destruction through the rabbit population of Australia, wild and domestic. Its clear from numerous field reports that vaccination with the currently available vaccine doesnt provide a lot of protection. Some people try to get around this through hyper-immunising their rabbits with more frequent doses. It may help a bit but we cant be sure. Losses at times have been sporadic an...d at other times quite dramatic. We dont know why the difference. As far as we know the government will officially release the other new strain (K5) in March to boost the control of wild rabbits. We cant be sure what impact it will have on vaccinated domestic rabbits. Some limited studies have shown a degree of cross-protection against K5 with the existing vaccine. On the other hand we experienced a series of field outbreaks in the greater Sydney area 2-3 years ago with a strain similar to K5, and at that time some of the affected rabbit owners claimed their vaccinated rabbits died. That strain seemed to disappear into the background when RHVD2 arrived on the scene. We will have to wait and see what happens when K5 is released, especially as it will be ongoing and at multiple sites around the country. Fingers crossed. We are working on making an improved vaccine available. We are exploring both options of local manufacture and import of an overseas vaccine. Progress is slow on both fronts but there is some progress. However its clear there wont be any new vaccine in time for the release of K5 in March. Red tape is our biggest obstacle with both options. There is not a lot more rabbit owners can do in the meantime other than use the existing vaccine, maybe more frequently, and keep their animals under as tight a quarantine as possible. Not easy with an insect born virus. Please find here a link to a recent Landline story on Calicivirus. Warning: parts of this footage may be disturbing to some viewers due to images of rabbit shooting and post-mortems. Other parts are disturbing due to images of a bald middle-aged vet. http://www.abc.net.au/landline/content/2016/s4453354.htm

22.01.2022 Suspect New Pigeon Disease Identified Interstate: The following notification has been made by pigeon racing authorities in Victoria: IMPORTANT NOTIFICATION There has been an outbreak of a highly infectious and deadly pigeon disease in Victoria and other States. Latest Laboratory tests have confirmed that it is NOT herpes-virus, adenovirus or pigeon paramyxovirus. Further tests are underway to identify the virus. It is advisable that all birds be locked down and the movement... of birds between flyers lofts should cease immediately. Further flyers should also avoid visiting other lofts at this time. Further information will be forwarded as it comes to hand. Regards, Stephen Kearsey 16th December 2016 David Crosbie Secretary Victorian Homing Association Incorporated. The disease was first seen in WA about 18 months ago. It seemed to settle down in that state after several months but recently turned up in Victoria, possibly in association with movement of pigeons interstate. Originally it was thought to be a type of adenovirus. However there seems to be some doubt about that now. To the best of our knowledge as of today 22/12/16, no cases have yet been confirmed in Sydney or NSW. However it is early days and the situation is quite fluid. Infectious diseases like this can be very contagious, as happened with PMV. Best to keep your loft isolated as recommended above.

19.01.2022 UPDATE ON PIGEON ROTAVIRUS A few weeks ago we sent three staff down to Latrobe University where they spent the best part of a week with Dr Travis Beddoe, going through the whole vaccine procedure from start to finish. We hadnt had the chance to do a proper technology transfer earlier because he had been overseas the whole time from when the research was first handed over to us until just recently. The team came away feeling much more positive about the whole procedure after ...their stint at Latrobe. Since then we have had to purchase some more equipment and raw materials to more closely match our procedure to that of the university, taking into account that as a commercial scale manufacturer we cant do everything exactly the same way it is done at a bench scale in a research lab. For example everything has to be up-scaled and there are a lot more regulatory constraints. We have commenced doing pilot runs again this last couple of weeks and the results are improved but still need some tweaking. Meanwhile our application for a permit from the APVMA has recently had its second assessment and the number of outstanding issues has been reduced from over 50 at the first attempt to less than 10 after the second. We are busily preparing our third dossier at present. There are complex internal issues within the APVMA that complicate this story about which we cant do much at present. Its been a long, hard, time-consuming, expensive journey to date but we are quietly confident that we are getting closer to the finish line.

14.01.2022 FOOTROT VACCINE AVAILABLE For the last few months our company has been supplying sheep footrot vaccine (Custom Footrot R-Pilus Vaccine). It is the strain specific recombinant product developed at the University of Sydney over the last several years. The vaccine requires the prior testing of a sample of sheep from each farm to determine which serogroups of the causative pathogen are prevalent. The vaccine is then custom mixed to suit the needs of each farm. The journey to maki...ng the vaccine commercially available has been long and arduous, worthy of the ordeals faced by Jason and the Argonauts in their search for the Golden Fleece. Instead of hydras, skeleton armies and sea monsters we have faced the scrutiny of regulatory agencies, more regulatory agencies, and still more regulatory agencies, not to mention all the other barriers to manufacturing in Australia. Congratulations to all our team for sticking to their guns and getting it over the line. Footrot vaccine research in Australia goes back to at least the time of Professor John Egerton at the University of Sydney. It developed further under Professor Richard Whittington and Dr Om Dhungyel. Various other research institutions and private companies have contributed along the way. We would like to take this opportunity to thank all those people who have dedicated time and energy to researching footrot vaccine and supporting diagnostics over the last two or three decades. We are also thinking of all the farmers, vets and contractors who did their backs in over the years paring feet amidst the heat, dust, flies and stench of footrot and chemical fumes. We hope we can now assist veterinarians and farmers get on top of this classical and awful disease of sheep and goats.

12.01.2022 Further Mareks Vaccine News for Breeders of Heritage and Hobby Poultry: Unfortunately the bad news continues that the usual fridge Mareks vaccine we supply to heritage and hobby chicken breeders is unavailable and likely to remain so for quite some time. There doesnt seem much chance it will be available for the coming spring breeding season. Its an imported vaccine, not one we make ourselves, and there isnt much we can do about it in the short to medium term. We do have ...a replacement frozen Mareks vaccine from another manufacturer. Some of you may remember using this vaccine before when the "fridge" vaccine was in short supply a few years ago. It is not as convenient to use as the "fridge" vaccine in that it has to be sent out on dry ice and then used up by the breeder before the dry ice runs out. So the chicks need to be ready to vaccinate more or less when it arrives. Unless you have your own access to liquid nitrogen storage, in which case you can store it for later. When using the vaccine, mixing of the frozen vaccine and the liquid diluent has to be done strictly according to directions. Then the vaccine needs to be used up within 6 hours. For customers far away we need to get dry ice in. It all needs a bit of organisation so call us to discuss first if you want to order. To make use of the "frozen" Mareks vaccine easier we have added the following video link link which explains the process in detail. https://www.youtube.com/watch?v=4oTLESLoJXY&feature=youtu.be

12.01.2022 Welcome to our brand new Facebook page. We intend to bring you interesting and reliable content over the next few months so that you can keep up to date with the health and management of your animals. News on Calicivirus in rabbits and Mareks disease vaccination in chickens is planned for uploading soon. All of us here wish you a Merry Christmas and a happy new year.

11.01.2022 Update on Pigeon Rotavirus Vaccine Our application for a Pigeon Rotavirus vaccine has been examined by the federal regulators who deal with animal medicines (APVMA). They have come back to us with a request for more information. Its perhaps not surprising as this is a relatively high tech vaccine. We are working to put together the dossier of extra information required as quickly as we can. Meanwhile we are also working on a number of technical issues with pilot batches of th...e vaccine, in conjunction with the university that did the initial research work. Its still not possible to say when the vaccine will be ready, other than to say it wont be ready in time for the federations who start racing in mid May. All we can do is keep working away at it as best we can and have it ready as soon as possible. Pigeon rotavirus is a new emergency disease in a small industry. The initial research work done at the university was rushed through with limited resources and minimal budget in an attempt to make some sort of vaccine available as soon as possible. We only have limited information at this time in regards to optimal usage of the vaccine, e.g., timing of shots, onset and duration of immunity. Furthermore our formulations arent exactly the same as the university. For the time being we will have to rely on general experience with other similar vaccines as regards usage instructions until we have a chance to do some trial work on the actual commercial vaccine in its final form. For the time being though our focus is on the vaccine itself and getting it out as soon as possible.

11.01.2022 Mareks Vaccine Update for Breeders of Heritage and Hobby Poultry: The bad news is that the usual fridge Mareks vaccine we supply to heritage and hobby chicken breeders is unavailable and likely to remain so for several months or even up to a year. The manufacturer has run out meaning there is none available in Australia and there is nothing anyone can do about it. The good news is that we have a replacement frozen Mareks vaccine from another manufacturer. However the rep...lacement vaccine is not as convenient to use in that it has to be stored here in deep freeze in liquid nitrogen, sent out on dry ice, and then used up by the breeder before the dry ice runs out. Mixing of the frozen vaccine and the liquid diluent has to be done strictly according to directions. Then the vaccine needs to be used up within 6 hours (used to be 1 hour). Some of you may remember using this vaccine before when the same thing happened a few years ago. If you live nearby and pick up your vaccines it may be best to bring dry ice with you. For others further away we need to get dry ice in. It all needs a fair bit of organisation so call us to discuss first if you want to order. Its the best we can do for at least the next few months. See more

10.01.2022 Pigeon Rotavirus Sydney... To Race or Not to Race, That is the Question The pigeon fraternity has been hit by two new viruses in the last few years. Its a terribly unfortunate thing to have happened and very undeserved. But what can we do but play the cards life deals out? With Rotavirus there are arguments for and against racing this year in Sydney. Most of these arguments on both sides have some sort of merit. The downside to not racing mainly relates to the damage this wo...Continue reading

09.01.2022 New Pigeon Virus Confirmed in Sydney. The new pigeon virus which has been causing problems interstate has now been definitely confirmed as being present in Sydney. Over the last week or 10 days we have had several people telling us they know of other people with sick pigeons with symptoms suggestive of the new virus. We received good quality suspect birds for testing late last week. Samples from these were sent to the Agribio lab in Melbourne as they have the most experience ...with this particular disease. The results came back positive for the new virus this afternoon. Since then we have received more birds for testing and it is very likely from their histories that these samples will also come back positive. Both fancy and racing lofts have been affected. Informal feedback from pigeon owners is that the virus is already widespread in Sydney. Furthermore the identification work on the virus has now been completed and it is being called a Rotavirus, which is a somewhat distant cousin of the Reovirus family. This type of virus is tough and can survive in the environment for long periods of time. It can spread on anything that comes into contact with the sick pigeons. Some of the birds we have looked at have had secondary E.coli infection in the main body organs as well. The best pigeon owners can do in the meantime is lock down their lofts and if the birds start to get sick: a) treat with Sulprim ("AVS Sulphur") or another brand of trimethoprim/ sulphadiazine ); b) possibly vaccinate with NDV4 live vaccine; and c) maintain good general care re hygiene, diet, stocking density, control of other diseases etc. From the experience interstate its likely the viirus will infect many lofts, but that after 5-7 days or so the birds in each loft that havent died will start to recover and return pretty much to normal.

08.01.2022 Brief Update on Pigeon Rotavirus in Sydney The virus seems to be spreading reasonably quickly around the Sydney area. Counting people who have brought birds in for checking here and others we have heard about second-hand we think there could be around 30-40 affected lofts. Racing and fancy birds affected. Mortalities from 5-50%. Still seeing E.coli lesions and positive cultures in some birds as well, especially in the sac around the heart. We dont know how the virus has spre...ad so quickly in only 2-3 weeks. The NSW DPI has decided to regard the virus as a significant emerging disease. That means they are willing to use public funds to pay for the testing to confirm the diagnosis and to investigate the virus a little further. What would normally be a few hundred dollars per case will now just be a handling fee at our end. So from now on we are sending samples to the NSW DPI Lab at Menangle (EMAI) rather than the Agribio Lab in Melbourne. We much appreciate the assistance we have had from Agribio to date. The EMAI Lab has a very strong virology department which may be able to assist with understanding the virus. The disease is not offically considered a notifiable disease in NSW. It hasnt been around long enough to be placed on any official list. That may happen down the track. But we are regarding it as an unofficial notifiable disease and notifying any confirmed cases to the DPI anyway. It doesnt mean that much as all they do is make a note of it. We wish we had better treatments to offer. Its like being back in the 1800s as we are fairly helpless in this regard. The treatments recommended to date seem to help a bit but not a lot, or at least the benefit seems to vary from loft to loft. Deveopment of a vaccine will not be easy. There are many bridges to cross with lots of unknowns. One of those is that if the disease settles down to a fair extent over time would there still be sufficient demand to make a vaccine viable to manufacture anyway? At this stage we dont know what the long term pattern of the disease is likely to be. In any case there isnt any chance of a vaccine before this race season. Even for next year there would need to be an organised effort soon and then luck would still be needed for the R&D of the vaccine to proceed smoothly. Vaccines are highly regulated and approvals can be slow and hard to get. On a positive note, at least the disease doesnt last long in each loft. Not sure at this stage about basic things like how long the virus hangs around for after that.

08.01.2022 Update on New Pigeon Disease Interstate Preliminary results of laboratory investigations into the new pigeon disease in Victoria suggests it is due to a reovirus. The results are still very provisional only and so may be revised over the next week or so. There is no specific treatment for pigeon reovirus or vaccine available in Australia at present. Its not known at this time where the virus came from. It may be the same virus that affected birds in WA but this is yet to be proven. Still very important to keep your loft as locked down as possible. Hopefully the picture will become clearer soon.

05.01.2022 Pigeon Rotavirus Vaccine Update We are doing our best to make the Pigeon Rotavirus Vaccine available ASAP. Cant give any absolute guarantee as to when that will be but we hope to have it available in time for next years racing season. That has always been our main plan and it still seems to be the most likely scenario at this time. Most of the work is still happening at the R&D level at Latrobe University in Melbourne. We are contributing our inputs into their work where appropriate. Once the R&D is complete it should hopefully only take a few weeks to manufacture a commercial batch. I think there is only a slim chance of vaccine being available in time for any part of this years racing season. In any case when it looks like getting close to being available we will definitely let everyone know.