Laboratory of Polypeptide Drugs and Delivery in Woolloongabba | Medical research centre

Laboratory of Polypeptide Drugs and Delivery

Locality: Woolloongabba

Phone: +61 7 3346 1869

Address: 20 Cornwall Street 4102 Woolloongabba, QLD, Australia

Website: http://moylelab.com

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23.01.2022 #UniversityofQueensland international #PhD #scholarship applications close Jan 17 2020 https://bit.ly/352Gk53. Looking for applicants to work on ARC #funded #genedelivery project. See http://moylelab.com for information and contact details

21.01.2022 Read our review on Modern Subunit Vaccines: Development, Components, and Research Opportunities (Moyle PM, Toth I. ChemMedChem 2013;8(3):360-76). A review of the current start of the art and future directions relating to the development of subunit vaccines.

21.01.2022 See our latest article on optimising #poly-L-lysine #dendrons for #GeneTherapy http://bit.ly/2a2QNGq

19.01.2022 Read our unit on 'Progress in Vaccine Development' in Current Protocols in Microbiology (Moyle PM. Curr Protoc Microbiol 2015;36:18.1.1-26). Includes: an introduction to different types of vaccines; techniques for identifying subunit antigens; vaccine delivery systems; and immunostimulatory adjuvants.

17.01.2022 Congratulations to Anjuman Begum for her recently accepted publication comparing the expression of the bombesin receptor on different cell lines to uptake of bombesin peptides. Link: https://goo.gl/B58mhc

17.01.2022 Congratulations to PhD student Zhenghui Xu on the submission of your thesis and the publication of your 1st research article in the prestigious Journal of Controlled Release. His publication describes a simple, efficient Sortase A enzyme-mediated means to site-specifically conjugate Toll-like receptor 2 agonist lipopeptide adjuvants onto recombinant protein antigens. https://doi.org/10.1016/j.jconrel.2019.11.018

16.01.2022 See our latest review on biotechnology approaches to produce potent, self-adjuvanting antigen-adjuvant fusion protein subunit vaccines in Biotechnology Advances http://www.sciencedirect.com//article/pii/S073497501730023X

16.01.2022 R. Bruce Merrifields automated peptide synthesizer revolutionized protein chemistry and helped him win the Nobel Prize in 1984. This early model was built with the help of Rockefellers instrument shop.

16.01.2022 Read our review on 'Modern Subunit Vaccines: Development, Components, and Research Opportunities' (Moyle PM, Toth I. ChemMedChem 2013;8(3):360-76). A review of the 'current start of the art and future directions' relating to the development of subunit vaccines.

13.01.2022 Australian Research Council (ARC) Grant Success: We thank the Australian Research Council and the Australian Government for awarding our laboratory and collaborators (Prof Toth, UQ) with a 2020 ARC Discovery Project Grant for 3 years. We look forward to the research and training opportunities that this funding will provide.... Project Summary: Developing a multicomponent platform for targeted gene delivery. Gene delivery systems are important tools in biological research and offer many exciting future prospects. Delivering gene material is very difficult in practice: rapid deterioration, poor cell uptake, and reaching the right tissue and cell types are major obstacles. Ways to overcome each barrier individually have been suggested in existing research but these components have not yet been combined in a single solution, which this project will tackle. This proposal aims to create a technology to stabilise and deliver active gene material to target cells. The gene delivery tool developed in this project will advance biological research greatly with many potential future applications. https://rms.arc.gov.au//a3f6be6e-33f7-4fb5-98a6-7526aa/208

13.01.2022 Congratulations to Zhenghui Xu on the acceptance and publication of his review on bioconjugation approaches to produce self-adjuvanting vaccines in Bioconjugate Chemistry http://pubs.acs.org/doi/abs/10.1021/acs.bioconjchem.7b00478

11.01.2022 PhD student Yu Wan's excellent review on how to improve the endosomal escape of gene therapies http://www.eurekaselect.com/134340/article

08.01.2022 Read about our exciting new breast cancer targeted siRNA/pDNA delivery platform http://www.sciencedirect.com//article/pii/S1742706117304142

07.01.2022 R. Bruce Merrifield’s automated peptide synthesizer revolutionized protein chemistry and helped him win the Nobel Prize in 1984. This early model was built with the help of Rockefeller’s instrument shop.

05.01.2022 Read our unit on Progress in Vaccine Development in Current Protocols in Microbiology (Moyle PM. Curr Protoc Microbiol 2015;36:18.1.1-26). Includes: an introduction to different types of vaccines; techniques for identifying subunit antigens; vaccine delivery systems; and immunostimulatory adjuvants.

03.01.2022 PhD student Yu Wans excellent review on how to improve the endosomal escape of gene therapies http://www.eurekaselect.com/134340/article

02.01.2022 Applications for University of Queensland (UQ) PhD Scholarships Information on applying for UQ PhD scholarships (IPRS, UQI) is available from: http://scholarships.uq.edu.au/ ... (through research higher degree link) other potential scholarship opportunities can be found at: http://www.uq.edu.au/pharmacy/dr-peter-moyle Laboratory Publications can be accessed through: ResearcherID: http://www.researcherid.com/rid/H-1536-2011 or ORCID: http://orcid.org/0000-0002-9247-681X

01.01.2022 Summer Research Scholarship Opportunities Applications for the UQ Summer Research Program 2016/17 open in mid July http://www.uq.edu.au/uqadvantage/summer-research... The Laboratory of Polypeptide Drugs and Delivery has opportunities available, see link below: